Adjuvants and Antibody Production: Dispelling the Myths Associated with Freund's Complete and Other Adjuvants
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چکیده
منابع مشابه
Adjuvants and antibody production: dispelling the myths associated with Freund's complete and other adjuvants.
Adjuvants have been used for more than 70 yr to enhance the immune response of the host animal to an antigen. Among the mechanisms that adjuvants use to enhance the immune response are the "depot" effect, antigen presentation, antigen targeting, immune activation/modulation, and cytotoxic lymphocyte induction. The immunostimulatory properties of adjuvants result in inflammation, tissue destruct...
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Pollard and J. M. Walker, eds. Clifton, N.J.: Humana Press. Reichmann, L., M. Clark, H. Waldmann, and G. Winter. 1988. Reshaping human antibodies for therapy. Nature 332:323-327. Reiter, Y., U. Brinkmann, K. O. Webber, SH. Jung, B. Lee, and I. Pastan. 1994. Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: Improved biochemical characteristics of recombinan...
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Nitrous oxide is a useful short-acting adjunct, which provides some analgesia in labor and is effective for procedural analgesia in adults and children in a wide variety of settings. Its adverse effects on vitamin B12, in particular with repeat exposure, require consideration and supplementation to avoid rare, but serious toxicity leading to bone marrow suppression and neuropathy. Continuous in...
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Immunologic adjuvants are agents that nonspecifically increase immune responses to specific antigens that are weakly immunogenic. The purpose of this article is to inform investigators and research staff about three commonly used and commercially available adjuvants for antibody production in laboratory animals and to briefly cover other adjuvants that may be used for this purpose. The three ad...
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Rhinophyma is a relatively common condition in the west of Scotland. The Canniesburn Plastic Surgery Unit receives 12 to 13 new patients per year for surgical treatment. The reported incidence of simultaneous carcinoma in the setting of rhinophyma is on the order of 15 to 30 percent. There are conflicting reports about the association between alcohol and rhinophyma in the literature, and these ...
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ژورنال
عنوان ژورنال: ILAR Journal
سال: 2005
ISSN: 1084-2020
DOI: 10.1093/ilar.46.3.280